Chymotrypsin

Introduction Chymotrypsin is also called chymotrypsinogen. Chymotrypsin is the endopeptidase extracted and separated from the fresh pancreas of cows (or pigs). Primary structure and spatial structure of α- Chymotrypsin have been clearly explained, which is a single peptide chain composed of 245...

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Product Details

Product Name

Chymotrypsin

Source: 

Bovine pancreas

Appearance

white crystalline powder

Storage Situation

Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Shelf Life

Two years when properly stored

Odor

odorless


Test items

Standard

Character

White or off-white crystalline powder or amorphous powder

Identification

Appear purple red

pH

5.5~7.0

Clarity and color of the solution

Solutions should be clear, colorless or almost colorless

Trypsin

≤1%

Loss on drying

≤5.0%

Residue on ignition

≤2.5%

Total amount of aerobe

≤1000CFU/g

Molds and yeast count

≤100CFU/g

Escherichia coli

Not detectable

Salmonella

Not detectable

Pseudomonas aeruginosa

Not detectable

Staphylococcus aureus

Not detectable

Potency determination

 It contains NLT 1000 USP Chymotrypsin Units/mg, calculated on the dried basis

Assay

90.0%~110.0%

Activity

≥1000u/mg


Introduction

Chymotrypsin is also called chymotrypsinogen.

Chymotrypsin is the endopeptidase extracted and separated from the fresh pancreas of cows (or pigs).

Primary structure and spatial structure of α- Chymotrypsin have been clearly explained, which is a single peptide chain composed of 245 amino acid residues, with 5 pairs of disulfide linkage in the molecule.

Chymotrypsin is white and light yellow crystal or amorphous powder, and easily soluble in the water, but insoluble in organic solvent. Relative molecular mass is 24000, and the optimum PH is 8~9.

Chymotrypsin is stable at a dry state, but will be quickly deactivated in water solution, most stable in the water solution with PH3~4. When it acts on the protein, Chymotrypsin will hydrolyze the peptide bond formed by the carboxyl of L-tyrosine and L-phenylalanine in priority


Function:

Thinning the viscous sputum, make it easy to expectoration, are effective both in purulent and non purulent sputum. Can also be used for wound healing after trauma or surgery.

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